Martin Stogniew Selected Research

TIC10 compound

12/2020	ONC201 and imipridones: Anti-cancer compounds with clinical efficacy.
11/2020	Biological activity of weekly ONC201 in adult recurrent glioblastoma patients.
10/2019	Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201.
1/2019	Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration.
10/2017	Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212.
8/2017	First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors.
11/2016	Discovery and clinical introduction of first-in-class imipridone ONC201.

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Martin Stogniew Research Topics

Disease

9	Neoplasms (Cancer) 12/2020 - 11/2016
3	Hematologic Neoplasms (Hematological Malignancy) 12/2020 - 11/2016
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2024 - 01/2022
2	Glioma (Gliomas) 12/2020 - 10/2019
2	Mycoses (Diseases, Fungus) 03/2009 - 02/2005
1	Major Depressive Disorder (Major Depressive Disorders) 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 12/2020
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 12/2020
1	Endometrial Neoplasms (Endometrial Cancer) 12/2020
1	Glioblastoma (Glioblastoma Multiforme) 11/2020
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2019
1	Skin Neoplasms (Skin Cancer) 10/2017
1	Melanoma (Melanoma, Malignant) 10/2017
1	Infections 09/2008
1	Invasive Fungal Infections 03/2007

Drug/Important Bio-Agent (IBA)

7	TIC10 compoundIBA 12/2020 - 11/2016
3	Anidulafungin FDA Link 03/2009 - 02/2005
2	methyloneIBA 01/2024 - 01/2022
2	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 01/2024 - 01/2022
2	TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA 12/2020 - 11/2020
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 12/2019 - 01/2019
2	ONC212IBA 12/2019 - 10/2017
2	EchinocandinsIBA 03/2009 - 02/2005
1	RNA (Ribonucleic Acid)IBA 01/2024
1	Antidepressive Agents (Antidepressants)IBA 01/2022
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2022
1	Dopamine Receptors (Dopamine Receptor)IBA 11/2020
1	dipinacoline glutamateIBA 10/2019
1	Peptide Hydrolases (Proteases)FDA Link 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	ONC206IBA 10/2017
1	LigandsIBA 11/2016
1	AzolesIBA 03/2009
1	GlycopeptidesIBA 09/2008
1	dalbavancinIBA 09/2008
1	Immunosuppressive Agents (Immunosuppressants)IBA 03/2007
1	Antifungal AgentsIBA 02/2005

Therapy/Procedure

2	Therapeutics 10/2019 - 11/2016
1	Oral Administration 01/2019